สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

NATIONAL INSTITUTE OF HEALTH OF THAILAND

Laboratory diagnosis of rabies patients

Authors : Sanit Kumperasart*, Sirima Pattamadilok*, Paijit Warachit**


Affililations:       *Virus Research Institute, Department of Medical Sciences

                        ** Department of Medical Sciences
           
Source:            Journal of Health Science 1997; 6(3): 535-539
           
Language:        Thai with English abstract
 
Abstract:
 
The objective of this study was to identify specimens sutitable for rabies diagnosis in human patients. Various sources of specimen e.g. saliva, urine hair follicles, serum and cerebrospinal fluid were collected from alive patients for laboratory investigation. Brain tissue was collected after death. The collected specimen were assayed for rabies antigen using fluorescent antibody technique. Rabies viruses were consequently isolated by mouse inoculation test. Level of antibody against rabies were determined in serum and cerebrospinal fluid using mouse neutralization test. This study suggested that saliva could be used for laboratory rabies diagnosis However, further study is necessary to carry on.