สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

National Institute of Health of Thailand

Authors : Paul A. Rota,1 Kevin Brown,3 Annette Mankertz,3 Sabine Santibanez,1 Sergey Shulga,4 Claude P. Muller,5 Judith M. Hu¨bschen,5 Marilda Siqueira,6 Jennifer Beirnes,7 Hinda Ahmed,8 Henda Triki,9 Suleiman Al-Busaidy,10 Annick Dosseh,11 Charles Byabamazima,12 Sheilagh Smit,13 Chantal Akoua-Koffi,14 Josephine Bwogi,15 Henry Bukenya,15 Niteen Wairagkar,16 Nalini Ramamurty,16 Patcha Incomserb,17 Sirima Pattamadilok,17 Youngmee Jee,18 Wilina Lim,19 Wenbo Xu,20 Katsuhiro Komase,21 Makoto Takeda,21 Thomas Tran,22 Carlos Castillo-Solorzano,23 Paul Chenoweth,1 David Brown,2 Mick N. Mulders,24 William J. Bellini,1 and David Featherstone25

 

Affiliations : 

1 World Health Organization (WHO) Global Specialized Laboratory, Atlanta, Georgia
2 WHO Global Specialized Laboratory, WHO Regional Reference Laboratory, European Region, London, United Kingdom
3 WHO Regional Reference Laboratory, European Region, Berlin, Germany
4 WHO Regional Reference Laboratory, European Region, Moscow, Russian Federation
5 WHO Regional Reference Laboratory, European Region, Luxembourg
6 WHO Regional Reference Laboratory, Region of the Americas, Rio De Janiero, Brazil
7 WHO Regional Reference Laboratory, Region of the Americas, Winnipeg, Canada
8 WHO Regional Office, Eastern Mediterranean Region, Cairo, Egypt
9 WHO Regional Reference Laboratory, Eastern Mediterranean Region, Tunis, Tunisia
10 WHO Regional Reference Laboratory, Eastern Mediterranean Region, Muscat, Oman
11 WHO Regional Office, African Region, Ouagadougou, Burkina Faso
12 WHO Regional Office, African Region, Harare, Zimbabwe
13 WHO Regional Reference Laboratory, African Region, Johannesburg, South Africa
14 WHO Regional Reference Laboratory, African Region, Abidjan, Cote d'Ivorie
15 WHO Regional Reference Laboratory, African Region, Entebbe, Uganda
16 WHO Regional Office Southeast Asian Region, Delhi, India
17 WHO Regional Reference Laboratory, Southeast Asian Region, Bangkok, Thailand
18 WHO Regional Office, Western Pacific Region, Manila, Philippines
19 WHO Regional Reference Laboratory, Western Pacific Region, Hong Kong
20 WHO Regional Reference Laboratory, Western Pacific Region, Beijing, China
21 WHO Global Specialized Laboratory, Tokyo, Japan
22 WHO Regional Reference Laboratory, Western Pacific Region, Victoria, Australia
23 WHO Regional Office, Region of the Americas, Washington, D.C
24 WHO Regional Office, European Region, Copenhagen, Denmark
25 WHO Headquarters, Geneva, Switzerland

Source :

The Journal of Infectious Diseases 2011;204:S514–S523

Language : English

Abstract :

 
 

      A critical component of laboratory surveillance for measles is the genetic characterization of circulating wildtype viruses. The World Health Organization (WHO) Measles and Rubella Laboratory Network (LabNet), provides for standardized testing in 183 countries and supports genetic characterization of currently circulating strains of measles viruses. The goal of this report is to describe the lessons learned from nearly 20 years of virologic surveillance for measles, to describe the global databases for measles sequences, and to provide regional updates about measles genotypes detected by recent surveillance activities. Virologic surveillance for measles is now well established in all of the WHO regions, and most countries have conducted at least some baseline surveillance. The WHO Global Genotype Database contains .7000 genotype reports, and the Measles Nucleotide Surveillance (MeaNS) contains .4000 entries. This sequence information has proven to be extremely useful for tracking global transmission patterns and for documenting the interruption of transmission in some countries. The future challenges will be to develop quality control programs for molecular methods and to continue to expand virologic surveillance activities in all regions.