สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

NATIONAL INSTITUTE OF HEALTH OF THAILAND

First isolation of Bartonella bovis from animals in French Guyana, South America

Authors : W. Saisongkorh1, L. Barrassi1, B. Davoust2, C.-A. de Broucker3, D. Raoult1 and J.-M. Rolain1
Affiliations : 

1 Universite´ de la Me´diterrane´e, Unite´ des Rickettsies, URMITE CNRS-IRD, UMR, Faculte´ de Me´decine et de Pharmacie, Marseille.
2 Direction Re´gionale du Service de Sante´ des Arme´es de Toulon.
3 Direction Interarme´es du Service de Sante´ des Arme´es de la Guyane, France.
          

Source :

Clinical Microbiology and Infection 2008: 10.1111/j.1469-0691.2008.02198.x

Language : English

Abstract :

 
 

          Bartonella species are intracellular parasites of several animals which are considered potential emerging pathogens in humans. In South America only a few data of Bartonella species has been reported. The objective was to detect, to isolate and to identify the presence of Bartonella species from blood of animals from French Guyana, South America. Among the five species of animals studied, 19 out of 27 blood culture positive from bovines were identified by DNA amplification and sequencing of the ITS gene represented a percentage of similarity ‡98% to B. bovis. In addition, we found a heterogeneity of susceptibility to fluoroquinolones, with ciprofloxacin was linked to an intrinsic mutation Ser-83 Ala (E. coli numbering) in the QRDR of the gyrA gene. Our findings demonstrate that B. bovis probably has a worldwide distribution in cattle (70%), with a high proportion of infected animals.