สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

NATIONAL INSTITUTE OF HEALTH OF THAILAND

No Proof of HTLV-I/II in intravenous drug abusers with a high rate of HIV-1 infection in central Thailand

Authors : Suranga Saguanwongse*, Amorntip Muangpom*, Nuanjun Ruchusatsawat*, Suthon Wongcheree*, Paijit Warachit*, Kikuko Miyamura*,**, Shudo Yamazaki** , Mitsuo Honda*,**

 

Affilications:       *Virus Reseaech Institute, Department of Medical Sciences, Nonthaburi 11000, Thailand
                        **AIDS Research Center, National Institute of Health, Shinjuku-ku,
Tokyo 162, Japan
           
Source:             Microbial Immunology 1996; 40(9): 639-644
 
Language:         English
 
Abstract:
 
Serum specimens of 1,074 intravenous drug abusers (IVDA) were examined for infection with HIV-1, HTLV-1 and HTLV-II in central Thailand. Three hundred and sixty-two of the specimens were seropositive for HIV-1 (33.7%). The HIV-1 seropositive IVDAs exhibited increased seropositivity with age through group 40-44 and significantly decreased seropositivity over the age of 45. In contrast, no seropositivity to either HTLV-I or-II was detected in the samples tested by a particle-agglutination assay for HTLV followed by type-specific Western blotting for HTLV. Reference to previous reports suggested that the rate of HIV infection in IVDAs has decreased with no HTLV-I or HTLV-II in Thailand when compared with that of the HIV infection in 1992.