สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

NATIONAL INSTITUTE OF HEALTH OF THAILAND

Norovirus and Sapovirus infection in Thailand

Authors : Ratigorn Guntapong*, Grant S. Hansman**,***, Tomoichiro Oka**, Satoko Ogawa**, Tsutomu Kageyama**, Yaowapa Pongsuwanna* and Kazuhiko Katayama**

 

Affiliation:      * National Institute of Health, Department of Medical Sciences
** Department of Virology II, National Institute of Infectious Diseases, Japan
***Department of Developmental Medical Sciences, The University of Tokyo, Japan
 
Source:         Japanese Journal of Infectious Diseases 2004; 57: 276-278
 
Language:     English
 
Abstract:
 
Stool specimens collected between November 2002 and April 2003 from hospitalized infants with acute gastroenteritis from four distinct geographical regions in Thailand were examined for norovirus (NoV) and sapovirus (SaV) by reverse transcription-PCR and sequence analysis. Of the 80 specimens examined, we identified 11 NoV and 9 SaV single infection, and 3 NoV/SaV mixed infections. The majority of NoV strains (64%) belonged to genogroup II/genotype 4 (GII/4;Lordsdale cluster). Other NoV strains co-circulating belonged to GII/1, GII/3, GII/6, and one new genotype cluster (GII/New). The majority of SaV strains (83%) were from the Manchester cluster. One isolated SaV strain represented a recently discovered novel genogroup within the SaV genus (SG-V), and another isolated SaV strain represented a novel SaV genogroup II cluster.