สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

NATIONAL INSTITUTE OF HEALTH OF THAILAND

Novel mosquito repellents derived from essential oils of plants in Thailand

Authors : Apiwat Tawatsin*, Usavadee Thavara*, Jaree Bansiddhi**, Prapai Wongsinkongman**, Tidarat Boonruad**, Narumon Komalamisra***, Mir S. Mulla****

 

Affiliations:     * National Institute of Health, Department of Medical Sciences, Ministry of Public Health, 88/7 Tiwanon Road, Nonthaburi 11000, Thailand
** Medicinal Plant Research Institute, Department of Medical Sciences, Ministry of Public Health, 88/7 Tiwanon Rd., Nonthaburi 11000, Thailand
*** Deparment of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
**** Department of Entomology, University of California, Riverside, CA 92521, U.S.A
 
Source:         Presented in the XXII International Congress of Entomology, Brisbane, Australia, 15 – 21 August 2004
 
Language:     English
 
Abstract:
 
Mosquito-borne diseases, such as dengue, malaria and filariasis are serious public health problems in many countries, especially in the tropical regions of the world. These diseases are caused by pathogens that are transmitted to man through mosquito biting only, thus personal protection from mosquito bites is then considered as one of the strategies to prevent them. Efforts to develop alternatives to replace chemical repellents have been increasingly considered, including extracting and evaluating plant products for repellent activity. The development and use of locally available plant products showing repellent activity thus avails an alternative strategy for prevention of mosquito-borne diseases. In this study we evaluated and reported repellent effects of essential oils extracted from plants against 4 mosquito vectors: Aedes aegypti, Ae. albopictus, Anopheles dirus and Culex quinquefasciatus under laboratory conditions using human volunteers. The essential oils were extracted from various parts of 22 plant species, belonging to 10 families, and the oils were prepared as 10% solution in absolute ethanol and some additives. The essential oils showing high degree of repellency were subsequently formulated as topical repellents and tested against day- and night-biting mosquitoes under field conditions. The results obtained from both laboratory and field evaluations will be presented.