สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

NATIONAL INSTITUTE OF HEALTH OF THAILAND

Local strain influenza virus isolated during the period 1998-1999

Authors : Pranee Thawatsupha*, Paiboon Maneewong*, Kanaungkid Prasittikhet*, Sunthareeya Waicharoen*,


Affiliations:
     
   *National Institute of Health, Department of Medical Sciences

           

Source:             Journal of Health Sciences 2000; 9(4): 551-557

           

Language:         English

 

Abstract:

 

From 1998 - 1999, the National Influenza Center, Department of Medical sciences collected throat swabs from outpatients with upper respiratory symptoms presenting at Health Center 17, Sammitivej Hospital and other hospitals. A total of 541 swabs were collected in 1998 and 372 in 1999. Of these, 257 (47.5%) and 152 (40.9%), respectively, were positive for influenza virus. Based on Immunofluorescence and hemagglutination inhibition testing, in 1998 we found 92 influenza type B and 165 influenza type A virus. Of the type A, we found 40 subtype H1N1, 114 subtype H3N2, and 11 untyped. In 1999, we found 78 influenza type B and 74 influenza type A viruses. Of the type A, we found 11 subtype H1N1, 56 subtype H3N2 and 7 untyped. The strains isolated in 1998 were A / Sydney / 5 /97 (H3N2) which was caused epidemics worldwide, A / South Africa / 1147 / 96 (H3N2) , A / Wuhan / 371 / 95' (H1N1), A / Beijing / 262 /95 (H1N1) and B / Beijing / 243 / 97, which was antigenically similar to B / Shangdong / 7 / 97. In 1999, the strains isolated were slightly different from those isolated in 1998. They included A / Moscow / 10 / 99 (H3N2) , A / New Caledonia / 20 / 99 (H1N1), B / Indiana / 1 / 95, B / Shangdong / 7 / 97 and B / Beijing / 184 / 93 , which is actually an old strain that re- circulated. The strains isolated in Thailand are very similar to the strains circulating worldwide and to the strains recommended by the World Health Organization for inclusion in the vaccines for 1998 - 1999 and 1999 - 2000.