สถาบันวิจัยวิทยาศาสตร์สาธารณสุข

National Institute of Health of Thailand

Authors : Duanthanorm Thawarananyha*, Kanittha Chimabutra**, Kruavon Balachandra*, Paijit Warachit*, Somsak Pantuwatana***, Reiko Inagi****, Takeshi Kurata*****, Koichi Yamanishi****


Affiliations:
        *National institute of Health, Department of Medical Sciences,

88/7 Tiwanon Road, Nonthaburi 11000, Thailand

**Charoenkrung Pracharak Metropolis Hospital, Bangkok, Thailand

***Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

****Department of Microbiology, Osaka University Medical School, Osaka University, Japan

*****Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan

 

Source:             Southeast Asian Journal of Tropical Medicine and Public Health

1999; 30(2): 259-264 

 

Language:         English

 

Abstract:

 

Prevalences of human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) DNA were investigated in normal Thai population. Peripheral blood mononuclear cells (PBMC) and saliva were collected from 238 healthy adults in five provinces which might be a representative of each part the country, and 120 normal children in one province. Prevalences of HHV-6 DNA PBMC were 45.5-74.3% in adults and 78.3% in children, and in saliva, very low prevalence were detected; 5.7-8.6% in adults and 15.0% in children, respectively. Additionally, all HHV-6 DNA detected in this study were variant B. Comparingly to those of HHV-7 DNA, the prevalences were significantly higher than those of HHV-6, ie, 82.9-91.4% in PBMC of adults, 85% in PBMC of children, 84.8-89.0% in saliva of adults and 92.5% in saliva of children. HHV-6 and HHV-7 isolation from saliva specimens were also performed. No HHV-6 could be isolated from any samples, whereas, in the present study, HHV-7 could be isolated as 90.0% from children and as 20.0-54.5%  from adults.